Status:
RECRUITING
The Application of Photosensitive Hydrogel in Intranasal Endoscopic Dacryocystorhinostomy
Lead Sponsor:
Eye & ENT Hospital of Fudan University
Conditions:
Chronic Dacryocystitis
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
To study the effect of Photosensitive hydrogel used for suture free anastomosis of lacrimal cyst and nasal mucoperiosteal flap in endoscopic nasal dacryocystostomy, and evaluate its adhesion to lacrim...
Detailed Description
After endoscopic dacryocystonasal anastomosis, granulation and/or cicatricial adhesion are the main reasons for surgical failure. How to achieve the ideal fit between the lacrimal sac flap and the nas...
Eligibility Criteria
Inclusion
- Voluntarily participate in this clinical study and sign the informed consent;
- Gender is not limited, age 18-75 years old;
- The patient had symptoms and signs of chronic dacryocystitis, and the results of lacrimal passage irrigation suggested that the lower rush and return or upper rush and lower return, accompanied by mucous or purulent discharge reflux;
- Lacrimal duct angiography suggests nasolacrimal duct obstruction without lacrimal canaliculi and/or duct obstruction.
Exclusion
- Age \< 18 or \> 75 years old;
- Previous history of dacryocystonasal anastomosis;
- Abnormal coagulation function;
- Tumors of lacrimal passage, especially in patients with papilloma or malignant tumors;
- in the acute dacryocystitis attack stage;
- obvious scar constitution;
- Complicated with serious nasal diseases, such as severe allergic rhinitis, chronic rhinosinusitis and nasal polyps, acute suppurative rhinosinusitis, severe atrophic rhinitis, and severe deviation of nasal septum;
- Have serious heart, liver, kidney, lung and other basic diseases, can not tolerate general anesthesia;
- Distance from the hospital, postoperative review is not convenient;
- Participated in other clinical trials within the last 3 months;
- Any medical history that the investigator determines may interfere with the test results or increase the patient's risk.
Key Trial Info
Start Date :
March 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06551766
Start Date
March 1 2023
End Date
December 31 2024
Last Update
August 13 2024
Active Locations (1)
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1
Eye & ENT Hospital of Fudan University
Shanghai, China, 200031