Status:

RECRUITING

Radioimmunotherapy in Solid Tumors (PNRR-MCNT2-2023-12378239-Aim2)

Lead Sponsor:

IRCCS San Raffaele

Collaborating Sponsors:

European Commission

Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale

Conditions:

Glioblastoma

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

This is a prospective multicenter study of hypofractionated radiotherapy for the radiation treatment (RT) of solid tumors and in particular for Glioblastoma (in Aim 2). It is based on the results of o...

Detailed Description

This is a prospective multicenter pilot study. Functional and spectroscopic neuroradiological imaging will be adopted for treatment planning. Specialized software will be used to perform radiomic feat...

Eligibility Criteria

Inclusion

  • Diagnosis of Glioblastoma.
  • ECOG performance score 0-2 (defined during the first visit)
  • Surgically removable lesion (according to the operability criteria established by the Neurosurgery Unit)
  • For healthy volunteers, people who are as comparable as possible with the patient population in terms of sex and age will be recruited

Exclusion

  • Previous stroke
  • Presence of another primary and/or metastatic tumor For healthy volunteers also, absence of primary and/or metastatic tumor

Key Trial Info

Start Date :

August 31 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 28 2027

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06551909

Start Date

August 31 2024

End Date

February 28 2027

Last Update

June 8 2025

Active Locations (1)

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1

IRCCS San Raffaele Scientific Institute

Milan, MI, Italy, 20132