Status:

RECRUITING

Cybersickness Prevention and Mitigation in Virtual Reality for Healthy Volunteers

Lead Sponsor:

National Human Genome Research Institute (NHGRI)

Conditions:

Healthy Volunteers

Virtual Reality

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

Background: People use virtual reality (VR) technology to play games, socialize, work, or receive medical care. Some people have "cybersickness" after using VR. Cybersickness is similar to motion sic...

Detailed Description

Study Description: This study involves investigation of a virtual reality (VR) experience intended to prevent cybersickness (similar to motion sickness and eye strain) from use of virtual reality equ...

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA:
  • In order to be eligible to participate in this study, an individual must meet all of the following criteria:
  • Provision of signed and dated informed consent form
  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • Aged 18-60
  • Ability to read, speak, and write in English
  • Normal or corrected-to-normal hearing
  • Normal vision or corrected-to-normal without use of glasses. Contact lenses for corrective purposes are acceptable.
  • Ability to read, speak and write in English is a requirement because the VR-based study materials and assessment are only available in English and several of the key questionnaires for the study are not validated in other languages.
  • EXCLUSION CRITERIA:
  • An individual who meets any of the following criteria will be excluded from participation in this study:
  • Reporting motion sickness propensity of 0, 9 or 10 on a 0-10 scale where 0 =never experience motion sickness and 10 = experience motion sickness very frequently (self-assessed by participants).
  • Reporting a history of photo-sensitive seizure disorders, vestibular disorders and/or other conditions that may make participants prone to nausea, dizziness, vertigo, ataxia, or incoordination.
  • Known pregnancy
  • Reporting current use of medication or supplements that inhibit nausea, e.g., Zofran/ondansetron, Phenergan/promethazine

Exclusion

    Key Trial Info

    Start Date :

    September 26 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    July 1 2026

    Estimated Enrollment :

    150 Patients enrolled

    Trial Details

    Trial ID

    NCT06552754

    Start Date

    September 26 2025

    End Date

    July 1 2026

    Last Update

    January 9 2026

    Active Locations (2)

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    Page 1 of 1 (2 locations)

    1

    Iowa State University

    Ames, Iowa, United States, 50011

    2

    National Institutes of Health Clinical Center

    Bethesda, Maryland, United States, 20892