Status:

RECRUITING

Spastic Paraplegia - Centers of Excellence Research Network

Lead Sponsor:

Boston Children's Hospital

Collaborating Sponsors:

Massachusetts General Hospital

Columbia University

Conditions:

Hereditary Spastic Paraplegia

Primary Lateral Sclerosis

Eligibility:

All Genders

Brief Summary

The Spastic Paraplegia - Centers of Excellence Research Network (SP-CERN) is a collaborative research consortium dedicated to advancing the understanding, diagnosis, and treatment of hereditary spasti...

Detailed Description

The hereditary spastic paraplegias (HSPs) include over 80 rare neurogenetic disorders, collectively representing the most prevalent cause of inherited spasticity and related disabilities globally. In ...

Eligibility Criteria

Inclusion

  • Male or female patients of all ages with a clinical and molecular diagnosis of hereditary spastic paraplegia type 4 (SPG4, SPAST) or hereditary spastic paraplegia type 5A (SPG5A, CYP7B1).

Exclusion

  • Not having such a diagnosis and/or not being related to such individual.

Key Trial Info

Start Date :

June 4 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 4 2027

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06553976

Start Date

June 4 2024

End Date

June 4 2027

Last Update

December 13 2024

Active Locations (11)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 3 (11 locations)

1

University of Miami Miller School of Medicine

Miami, Florida, United States, 33136

2

University of Iowa Carver College of Medicine

Iowa City, Iowa, United States, 52242

3

Boston Children's Hospital

Boston, Massachusetts, United States, 02215

4

Massachusetts General Hospital

Boston, Massachusetts, United States, 02215