Status:

RECRUITING

Local vs Systemic Methotrexate in Management of Uterine Ectopic Pregnancy

Lead Sponsor:

Tanta University

Conditions:

Local

Systemic

Eligibility:

FEMALE

20-40 years

Phase:

NA

Brief Summary

This study aims to compare local and systemic methotrexate in the management of uterine ectopic pregnancy regarding the duration of beta human chorionic gonadotropin (hCG) clearance and need for furth...

Detailed Description

Ectopic pregnancy is considered a life-threatening condition which requires immediate intervention. Owing to the advancements in medical technology, ectopic pregnancy can now be diagnosed in the early...

Eligibility Criteria

Inclusion

  • Age from 20 to 40 years.
  • Women with uterine ectopic pregnancy (interstitial pregnancy, cervical pregnancy, or cesarean scar pregnancy).
  • Gestational age is less than 9 weeks, the embryo size is smaller than 10 mm, and the serum beta-human chorionic gonadotropin (β-hCG) levels are less than 10,000 mIU/mL.

Exclusion

  • Patients with basal beta hCG levels less than 1500 mIU/Ml.
  • Any contraindications to MTX as a hepatic disorder, renal disorder and thrombocytopenia
  • Diabetes mellitus.
  • Severe vaginal bleeding or hemodynamic changes or hemoperitoneum.
  • History of cancer.
  • Ascites.
  • Pleural effusion.

Key Trial Info

Start Date :

August 15 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2025

Estimated Enrollment :

34 Patients enrolled

Trial Details

Trial ID

NCT06554470

Start Date

August 15 2024

End Date

July 1 2025

Last Update

August 16 2024

Active Locations (1)

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Tanta University

Tanta, El-Gharbia, Egypt, 31527