Status:
COMPLETED
Topical 1% Methotrexate Gel Versus Clobetasol Propionate in Patients With Psoriasis
Lead Sponsor:
Dr. Jose N. Rodriguez Memorial Hospital and Sanitarium
Conditions:
Pilot Study
Psoriasis
Eligibility:
All Genders
18+ years
Phase:
EARLY_PHASE1
Brief Summary
A pilot study on the formulation of topical methotrexate was conducted. Patients after baseline evaluation were randomly placed into either topical 1% methotrexate gel or clobetasol propionate 0.05% o...
Detailed Description
This is a pilot study done for a year at the dermatologic clinic of a tertiary hospital. The study was approved by the Institutional Review Board and followed the declaration of Helsinki Principles fo...
Eligibility Criteria
Inclusion
- patients with stable mild-moderate plaque psoriasis, regardless of chronicity of the disease,
- involving less than 30% of the body surface area (BSA)
- negative pregnancy test for female participants of reproductive age
Exclusion
- patients with psoriatic lesions on the face and/or scalp,
- administration of topical, systemic, or intralesional therapy or UV radiation therapy for at least 2 weeks before the study.
- Patients with deranged laboratory results at the baseline of the study, minors or lactating mothers
- patients planning a pregnancy with their spouses/partners in the next three months.
Key Trial Info
Start Date :
January 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2023
Estimated Enrollment :
2 Patients enrolled
Trial Details
Trial ID
NCT06555497
Start Date
January 1 2022
End Date
December 31 2023
Last Update
August 16 2024
Active Locations (1)
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1
Dr. Jose N. Rodriguez Memorial Hospital and Sanitarium
Caloocan City, National Capital Region, Philippines, 1427