Status:

RECRUITING

Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease

Lead Sponsor:

Boston Children's Hospital

Collaborating Sponsors:

National Institutes of Health (NIH)

Conditions:

Sickle Cell Disease

Eligibility:

All Genders

12-25 years

Phase:

NA

Brief Summary

Adolescents and young adults with sickle cell disease (SCD) face challenges managing their illness and maintaining their well-being. This study proposes to test the feasibility and acceptability of a ...

Detailed Description

Adolescents and Young Adults (AYAs) with blood disorders are at risk for poor physical, psychological, and social outcomes. Sickle Cell Disease (SCD) is a life-limiting condition, defined as a group o...

Eligibility Criteria

Inclusion

  • Aged ≥ 12 and ≤ 25 years of age at baseline
  • Diagnosed with Sickle Cell Disease (HbSS, HbSC, HbS-Beta Thalassemia, and other related hemoglobinopathies)
  • Receiving Medical Care at the DFCI/BCH Blood Disorders Center.
  • Scored \> 9 on Patient Health Questionnaire 9-item (PHQ-9) or Generalized Anxiety Disorder (GAD)
  • Able to speak English or Spanish language (for PRISM sessions)
  • Able to read English or Spanish language (for completion of surveys)
  • Cognitively able to participate in PRISM sessions and complete written questionnaires and surveys, as judged by the site investigator
  • Willing and able to adhere to the study visit schedule and other protocol requirements

Exclusion

  • \* does not meet above criteria

Key Trial Info

Start Date :

October 23 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2030

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT06555939

Start Date

October 23 2025

End Date

September 1 2030

Last Update

December 10 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Boston Children's Hospital

Boston, Massachusetts, United States, 02115