Status:

NOT_YET_RECRUITING

Analysis of Nasopharyngeal Microbiota in Patients With Respiratory Infections

Lead Sponsor:

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Conditions:

Respiratory Infection

Eligibility:

All Genders

Up to 20 years

Brief Summary

Respiratory tract infections represent the most frequent infectious pathology in community environments and when of bacterial origin, imply a morbid state generally supported by a pathogenic bacterial...

Detailed Description

In recent years, the microbiota of the upper airways has emerged as a further factor influencing the susceptibility, frequency and severity of acute respiratory diseases. Greater knowledge of it, also...

Eligibility Criteria

Inclusion

  • age 0-20 years
  • signs and/or symptoms of acute respiratory tract infection such as cold, pharyngitis, laryngitis, tracheitis, otitis, epiglottitis, laryngotracheitis, bronchitis and pneumonia.

Exclusion

  • antibiotic therapies in the last 30 days
  • treatments with prebiotics or probiotics in the last 60 days (in particular containing Streptococcus salivarius)
  • hormone therapies in the last 60 days
  • local therapies in the last 60 days
  • treatments with oral cavity disinfectants in the last 30 days
  • presence of other pre-existing or ongoing respiratory pathologies
  • current severe sepsis (sepsis criteria + organ dysfunction, peripheral hypoperfusion, hypotension)

Key Trial Info

Start Date :

September 15 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 15 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06556420

Start Date

September 15 2024

End Date

August 15 2026

Last Update

August 16 2024

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