Status:

RECRUITING

G.I. Pharmacokinetics of LMN-401 in Individuals With Ileostomies

Lead Sponsor:

Lumen Bioscience, Inc.

Conditions:

Travelers Diarrhea

Eligibility:

All Genders

19+ years

Phase:

EARLY_PHASE1

Brief Summary

The goal of this interventional study is to learn about the intraluminal pharmacokinetics (PK) of the investigational drug LMN-401 in adult healthy volunteers with ileostomies. LMN-401 is being develo...

Eligibility Criteria

Inclusion

  • Aged 19 years and above
  • Medically stable
  • Mature and stable ileostomy (no revisions in past 6 months)
  • Willing and able to participate in all study visits
  • Willing and able to provide informed consent

Exclusion

  • Unable or unwilling to provide adequate informed consent
  • Gastroparesis
  • Using or planning to use anti-diarrheal medication
  • Using or planning to use opioids
  • Clinically significant disease
  • Women who are pregnant, intending to become pregnant, or breastfeeding
  • Non-English speakers

Key Trial Info

Start Date :

December 4 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 2 2025

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT06556940

Start Date

December 4 2024

End Date

December 2 2025

Last Update

January 9 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Coastal Digestive Health Research Institute Pty Ltd

Maroochydore, Australia, 4558