Status:

COMPLETED

Safety and Efficacy Predimenol for Headache

Lead Sponsor:

Dexa Medica Group

Collaborating Sponsors:

Fakultas Kedokteran Universitas Indonesia

Conditions:

Headache

Eligibility:

All Genders

18-60 years

Phase:

PHASE2

Brief Summary

This is a prospective, double-blind, placebo-controlled and randomized study aimed to obtain a description of the efficacy and safety of Predimenol in alleviating headache.

Detailed Description

Predimenol is a bioactive fraction extracted from Phaleria macrocarpa pericarpium (Mahkota Dewa). There will be 20 subjects per group (a total of 60 subjects) planned to be enrolled in the study. Th...

Eligibility Criteria

Inclusion

  • Healthy men or women aged 18 to 60 years with acute moderate tomoderate-severe headache.
  • Signing the informed consent.

Exclusion

  • Body temperature of \>37.3˚C and/or refuse to follow health protocol for COVID-19.
  • Known hypersensitivity to herbal drugs.
  • Pregnant or lactating women.
  • Have received any analgesic or anti-inflammatory drugs within the past 12 hours.
  • Presence of vomiting or diarrhea within the past 24 hours or still ongoing at the start of study.
  • Severe illness, e.g. severe hypertension, or any known organic diseases that may cause headache.

Key Trial Info

Start Date :

June 19 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 15 2024

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06558006

Start Date

June 19 2024

End Date

October 15 2024

Last Update

February 7 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Imeri Fkui

Jakarta Pusat, DKI Jakarta, Indonesia, 10430

2

Klinik Satelit Makara UI Depok

Depok, West Java, Indonesia