Status:

NOT_YET_RECRUITING

Prevention of Chronic Lung Disease (CLD - Prevention Study)

Lead Sponsor:

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Collaborating Sponsors:

Azienda Ospedaliera Universitaria Policlinico "G. Martino"

Azienda Ospedaliero-Universitaria di Parma

Conditions:

Chronic Lung Disease

Eligibility:

All Genders

1-24 years

Phase:

NA

Brief Summary

Primary endpoint: \- prospectively identify potential biomarkers able to predict the severe course of pulmonary funcion in the first 12 months of life and realize a new profile to early identify hugh...

Detailed Description

Background Chronic Lung Disease (CLD) is one of the most common complications of perinatal lung injury which represents a systemic condition with long term sequelae, such as persistent pulmonary dysfu...

Eligibility Criteria

Inclusion

  • Infants with gestational age \< 32 weeks with at least one of the following signs of acute respiratory failure within the first 24 hours of life:
  • need for mechanical ventilation;
  • need for noninvasive respiratory support;
  • need for oxygen administration;
  • need for surfactant administration

Exclusion

  • Congenital malformations
  • Neuromuscular diseases.

Key Trial Info

Start Date :

September 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2026

Estimated Enrollment :

42 Patients enrolled

Trial Details

Trial ID

NCT06559670

Start Date

September 1 2024

End Date

September 1 2026

Last Update

August 19 2024

Active Locations (1)

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Fondazione Policlinico Universitario Agostino Gemelli IRCCS UOC Neonatologia

Rome, RM, Italy, 00168