Status:

COMPLETED

JAK Inhibitors' Efficacy in Bullous Pemphigoid

Lead Sponsor:

Chao Ji

Conditions:

Bullous Pemphigoid

Janus Kinase Inhibitor

Eligibility:

All Genders

Brief Summary

Bullous pemphigoid (BP) is an autoimmune subepidermal blistering skin disease that predominantly affects the elderly population, with rare cases reported in children and adolescents. BP is characteriz...

Detailed Description

This study will conduct a retrospective review of patients with Bullous pemphigoid in the Department of Dermatology of the First Affiliated Hospital of Fujian Medical University. Researchers will init...

Eligibility Criteria

Inclusion

  • Diagnosis of Bullous pemphigoid;
  • Moderate to severe bullous pemphigoid; The disease severity was measured using the Bullous Pemphigoid Disease Area Index (BPDAI) score and was classified into mild (BPDAI ≤ 19), moderate (20 ≤ BPDAI ≤ 56), and severe (BPDAI ≥ 57).
  • Moderate to severe BP received JAK Inhibitors combination with corticosteroids therapy;

Exclusion

  • Patients diagnosed with malignant neoplasms
  • Previous administration with biologics within 3 months

Key Trial Info

Start Date :

January 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 31 2024

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT06561256

Start Date

January 1 2022

End Date

July 31 2024

Last Update

September 5 2024

Active Locations (1)

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1

The First Affiliated Hospital of Fujian Medical University

Fujian, Fuzhou, China, 350000