Status:
COMPLETED
Ventilator Settings for Bronchoscopy During Mechanical Ventilation: a Randomized Controlled Study
Lead Sponsor:
Centre Hospitalier Arras
Conditions:
Mechanical Ventilation Complication
Fiberoptic Bronchoscopy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Fiberoptic bronchoscopy (FOB) can cause a significant increase in respiratory resistances and airway pressure during mechanical ventilation (MV), which can jeopardize the delivery of the ventilatory a...
Detailed Description
Introduction : Fiberoptic bronchoscopy (FOB) during mechanical ventilation (MV) is a challenging procedure as it considerably reduces the endotracheal tube internal diameter, increasing respiratory re...
Eligibility Criteria
Inclusion
- Age ≥18 years;
- Acute respiratory failure requiring invasive mechanical ventilation in the intensive care unit;
- Indication of either a fiberoptic bronchoscopy (FOB) procedure or a percutaneous tracheostomy under FOB control;
- Patient under sedation with Richmond Agitation and Sedation Scale(RASS) ≤-2,
- Written informed consent obtained by the patient or the patient legal representative
Exclusion
- Presence of an absolute contraindication to FOB (respiratory arrest, severe acute respiratory distress syndrome (ARDS), refractory shock, uncontrolled heart rhythm disorder);
- Patients in respiratory distress or with severe patient-ventilator desynchronies ;
- Patients refusing FOB;
- Pregnancy ;
- Moribund patients (according to American Society of Anesthesiologists (ASA) Physical status score classification, class 5: high probability of death within 24 hours) or at high risk of death during the FOB procedure;
- Patients deprived of liberty;
- Patients under curators or guardianship.
Key Trial Info
Start Date :
September 10 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 19 2025
Estimated Enrollment :
46 Patients enrolled
Trial Details
Trial ID
NCT06562725
Start Date
September 10 2024
End Date
June 19 2025
Last Update
July 8 2025
Active Locations (1)
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1
Arras Hospital
Arras, France, France, 62000