Status:
RECRUITING
Magnesium Sulfate in Children Undergoing Laparoscopic Appendectomy
Lead Sponsor:
Medical University of Warsaw
Conditions:
Opioid Consumption
Multimodal Analgesia
Eligibility:
All Genders
18-18 years
Phase:
PHASE4
Brief Summary
Magnesium sulfate is one of the most commonly used co-analgetics. Its antinociceptive effect is related to antagonizing NMDA (N-methyl-D-aspartate) receptors of the nervous system, has an anti-inflamm...
Detailed Description
Pain in the perioperative period is associated with surgical stimuli but also with laryngoscopy and intubation. According to the currently applicable ERAS (Enhanced Recovery After Surgery) doctrine, t...
Eligibility Criteria
Inclusion
- ASA (American Society of Anesthesiologists) physical status class 1E, 2E, 3E (E - emergency)
- Patients undergoing laparoscopic appendectomy
Exclusion
- Allergy to the magnesium sulfate or the excipient
- Hypermagnesemia
- Renal failure (GFR \<30 ml/min)
- Myasthenia gravis
- Preoperative atrioventricular block
- Hypotension
- The use of digitalis glycosides
- The use of oral anticoagulants
- ASA physical status class 4E or higher
- Chronic treatment with analgesics
- Legal guardians or patient refusal
Key Trial Info
Start Date :
September 9 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2027
Estimated Enrollment :
188 Patients enrolled
Trial Details
Trial ID
NCT06563349
Start Date
September 9 2024
End Date
October 1 2027
Last Update
November 12 2024
Active Locations (1)
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1
Uniwersity Clinic Centre of Medical Uniwersity of Warsaw
Warsaw, Poland, 02-091