Status:

RECRUITING

A Cohort Study of Hereditary Ovarian Cancer Risk Prediction Models and Pathogenesis Exploration

Lead Sponsor:

Peking University Third Hospital

Conditions:

Ovarian Neoplasms

Eligibility:

FEMALE

18+ years

Brief Summary

The aim of this project is to establish a bidirectional multicenter cohort of hereditary ovarian cancer and to describe the clinicopathologic features of hereditary ovarian cancer patients in our coun...

Detailed Description

About 10%-20% of ovarian cancers have familial aggregation, suggesting that it may be hereditary ovarian cancer. Exploring a genetic ovarian cancer risk prediction model suitable for Chinese people wi...

Eligibility Criteria

Inclusion

  • Epithelial ovarian cancer
  • ≥18 years
  • The pathological diagnosis was clear
  • The genetic test showed germ line pathogenic/suspected pathogenic mutations (for mutation interpretation, refer to the American ACMG Classification Standards and Guidelines for Genetic Variation)

Exclusion

  • Non-epithelial ovarian cancer was confirmed by pathology
  • No genetic test has been performed

Key Trial Info

Start Date :

January 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT06564428

Start Date

January 1 2024

End Date

December 31 2026

Last Update

June 18 2025

Active Locations (1)

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Peking University Third Hospital

Beijing, Beijing Municipality, China, 100000