Status:

RECRUITING

ImmunoBoost: The Lymphatic Osteopathic Manipulative Treatment Protocol Study

Lead Sponsor:

Western University of Health Sciences

Collaborating Sponsors:

American Osteopathic Foundation

Conditions:

Healthy

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The goal of this clinical trial is to determine whether osteopathic manipulative treatment (OMT) enhances immune system readiness in healthy adults compared to exercise or sham light treatment. Specif...

Detailed Description

This clinical trial is a follow-up on a recent trial demonstrating an enhanced immune response in participants who received lymphatic osteopathic manipulative treatment (OMT) with each of their COVID-...

Eligibility Criteria

Inclusion

  • Individuals must be 18 years or older.
  • Individuals must provide informed consent.
  • Individuals must be healthy with a BMI under 30, with no primary or secondary immune deficiency or autoimmune disease/must not be immunocompromised.
  • Individuals must not be using or recently have used any immune-altering medications such as corticosteroids, cyclosporin, tacrolimus, and pimecrolimus
  • Individuals must not have had lymphatic OMT or other physical manipulation such as acupuncture, physical therapy, chiropractic, or massage therapy in the previous four weeks before study enrollment.
  • Individuals must have the ability to receive OMT with lymphatic techniques.
  • Individuals must be able to tolerate 12 minutes of moderate physical activity.
  • Individuals must not be pregnant or breastfeeding.
  • Individuals must not have had a splenectomy or other spleen or oncologic surgery within the past 6 months.
  • Individuals must be infection-free for the past 6 weeks before starting the study and have not received any immunizations within the past 6 weeks.
  • Individuals must be willing to avoid strenuous activity at least 24 hours before each visit.
  • Individuals must be willing to abstain from moderate to intense activity in the 4 hours between their 2nd blood draw and their final blood draw at each of their three visits.

Exclusion

  • Individuals are younger than 18 years of age.
  • Individuals who do not provide informed consent.
  • Individuals with a BMI over 30, or with primary or secondary immune deficiency or autoimmune disease or is immunocompromised.
  • Individuals using or recently have used any immune-altering medications such as corticosteroids, cyclosporin, tacrolimus, and pimecrolimus
  • Individuals who have had lymphatic OMT or other physical manipulation such as acupuncture, physical therapy, chiropractic, or massage therapy in the previous four weeks before study enrollment.
  • Individuals who don't have the ability to receive OMT with lymphatic techniques.
  • Individuals who cannot tolerate 12 minutes of moderate physical activity.
  • Individuals who are pregnant or breastfeeding.
  • Individuals who have had a splenectomy or other spleen or oncologic surgery within the past 6 months.
  • Individuals who have had an infection in the 6 weeks before starting the study and or have received any immunizations within the past 6 weeks.
  • Individuals not willing to avoid strenuous activity at least 24 hours before each visit.
  • Individuals not willing to abstain from moderate to intense activity in the 4 hours between their 2nd blood draw and their final blood draw at each of their three visits.

Key Trial Info

Start Date :

July 14 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 30 2025

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06565065

Start Date

July 14 2025

End Date

December 30 2025

Last Update

July 17 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Western University of Health Sciences

Pomona, California, United States, 91766

2

Western University of Health Sciences

Pomona, California, United States, 91766

ImmunoBoost: The Lymphatic Osteopathic Manipulative Treatment Protocol Study | DecenTrialz