Status:

COMPLETED

Evaluation of the Performance and Safety of the Aktiia Spot-check Optical Blood Pressure Monitoring Device At Wrist Against Double Auscultation

Lead Sponsor:

Aktiia SA

Conditions:

Hypertension

Eligibility:

All Genders

22-59 years

Phase:

NA

Brief Summary

This study, with N = 85 participants minimum over 3 visits spread over 23 hours, has been designed to assess the accuracy and precision of the Blood Pressure and pulse rate values as generated by Akti...

Eligibility Criteria

Inclusion

  • Participants must be able to provide an informed consent to participate.
  • Participant must be willing and able to comply with all of the study procedures and return for a day 2 visit.
  • Participants must be 22 to 59 years of age.
  • Participant or witness must be able to read or write in English.

Exclusion

  • Participants with compromised circulation, injury, or physical malformation of the equipment test sites or other sensor sites which would limit the ability to test sites needed for the study. (Note: Certain malformations may still allow participants to participate if the condition is noted and would not affect the sites utilized.)
  • Female participants who are known to be pregnant or who are trying to get pregnant confirmed by a day 1 positive urine pregnancy test unless the study participant is known to be not of child-bearing potential.
  • Participants with known clotting disorders or currently taking a prescription blood thinner.
  • Other known health conditions that will prevent safe participation in the study upon disclosure in Health Assessment Short Form or verbally.
  • Participants suffering from sustained cardiac arrhythmias that can lead to weak or unstable pressure pulses including tachycardia (heart rate at rest \> 120bpm) and atrial fibrillation.
  • Participants suffering from pathologies that systematically reduce peripheral perfusion including Raynaud's disease, diabetes, renal dysfunctions (eGFR \< 60mL / min / 1.73 m2), hyper- / hypothyroidism, pheochromocytoma or arteriovenous fistula.
  • A wrist circumference below 14 cm or above 23 cm.
  • An upper arm circumference \< 22cm or \> 42cm.
  • Any subject that, in the opinion of the investigator, does not exhibit any phenotype relevant to the objectives of this study.
  • Any condition or circumstance that, in the opinion of the investigator, may preclude study completion, interfere with accurate data collection, bias the results, by instance a subject presenting a lateral Blood Pressure difference at screening of more than 15 mmHg for the systolic and/or more than 10 mmHg for the diastolic.

Key Trial Info

Start Date :

September 23 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 10 2025

Estimated Enrollment :

140 Patients enrolled

Trial Details

Trial ID

NCT06565780

Start Date

September 23 2024

End Date

January 10 2025

Last Update

February 18 2025

Active Locations (1)

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1

Parameters Research Laboratory

Broomfield, Colorado, United States, 80021