Status:
RECRUITING
Avoidance-driven Decision Making and Learning in Anorexia Nervosa and Bulimia Nervosa
Lead Sponsor:
University of California, San Diego
Conditions:
Bulimia Nervosa
Anorexia Nervosa
Eligibility:
FEMALE
18-39 years
Brief Summary
The purpose of this study is to investigate areas of the brain responsible for avoidance learning in adults with eating disorders using brain imaging techniques, computer tasks, and self-report questi...
Eligibility Criteria
Inclusion
- Eating Disorder Group:
- Between the ages of 18 and 39 years old
- Meet DSM-V criteria for anorexia nervosa or bulimia nervosa
- Healthy Controls:
- Between the ages of 18 and 39 years old
- Have maintained 85% to 120% ideal body weight since menarche
Exclusion
- Psychotic illness/other mental illness requiring hospitalization
- Current dependence on drugs or alcohol defined by DSM IV criteria. Additionally, positive test results for drug use on the day of the scan, apart of marijuana, will result in cancelling or rescheduling the scan because acute use will impact MRI measures.
- Physical conditions (e.g. diabetes mellitus, pregnancy) known to influence eating or weight
- Neurological disorder, neurodevelopmental disorder, or history of head injury with \>30 min loss of consciousness
- Any contraindication to undergoing an MRI
- Primary obsessive compulsive disorder or primary major depressive disorder
- Additional Exclusion Criteria for ED Group:
- If taking other psychotropic medication, any change in dosage in the 2 weeks before scanning
- Additional Exclusion Criteria for Healthy Control Group:
- Meet criteria for the diagnosis of any psychiatric disorder currently
- Any history of binge eating or purging behaviors, including self-induced vomiting, laxative or diuretic misuse
- Use of any psychoactive or other medication known to affect mood or concentration in the last 3 months
Key Trial Info
Start Date :
August 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 31 2027
Estimated Enrollment :
78 Patients enrolled
Trial Details
Trial ID
NCT06566612
Start Date
August 1 2024
End Date
July 31 2027
Last Update
December 6 2024
Active Locations (1)
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1
UCSD Eating Disorders Treatment and Research Program
La Jolla, California, United States, 92121