Status:
RECRUITING
Emotion Processing Among Patients With ALS
Lead Sponsor:
University of Aarhus
Collaborating Sponsors:
Aarhus University Hospital
Aalborg University Hospital
Conditions:
Amyotrophic Lateral Sclerosis
Neuromuscular Diseases
Eligibility:
All Genders
18+ years
Brief Summary
The goal of this observational study is to learn about the emotional perception in people with ALS disease compared to people with other neuromuscular disease and healthy controls. The main questions ...
Detailed Description
Mild cognitive and behavioral changes occur in 35% of ALS patients and 10-15% of patients meet the criteria for FTD1-4. Recent research suggests changes in emotional perception and social cognition ar...
Eligibility Criteria
Inclusion
- ALS patients, ambulant and hospitalized
- Able to give informed consent
- Diagnosed with ALS or probable ALS according to the existing revision of the El Escorial Criteria 21,22.
- Patients with a peripheral neuromuscular disease, ambulant and hospitalized
- Able to give informed consent
- Diagnosed with a peripheral neuromuscular disease, that does not affect CNS, including but not limited to Myasthenia Gravis and polyneuropathy
- Healthy controls
- Able to give informed consent
- Age and gender matched to ALS patients
Exclusion
- All Participants
- Other severe medical, neurological, or psychiatric disorders
- Visual impairment to an extent that interferes with the ability to perform of the test
- Severe motor or cognitive deficits, to the extent that the test-task cannot be performed
- Alcohol or drug abuse to an extent the interferes with task performance
- Patients with a peripheral neuromuscular disease
- ● Familial predisposition to ALS
- Healthy controls
- Familial predisposition to ALS (first degree relatives)
- Medical treatment that affects the central nervous system (e.g., antidepressants)
Key Trial Info
Start Date :
December 15 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2026
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT06566651
Start Date
December 15 2023
End Date
June 30 2026
Last Update
August 22 2024
Active Locations (2)
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1
Aarhus University Hospital
Aarhus, Central Jutland, Denmark, 8200
2
Aalborg University Hospital
Aalborg, Region Nordjulland, Denmark, 9000