Status:

COMPLETED

Evaluation of the Effect of Non-Surgical Periodontal Treatment in Women With Polycystic Ovary Syndrome

Lead Sponsor:

Bezmialem Vakif University

Conditions:

Polycystic Ovary Syndrome

Gingivitis

Eligibility:

FEMALE

18-40 years

Phase:

NA

Brief Summary

The goal of this clinical trial is to compare women with polycystic ovary syndrome and systemically healthy woman in relation to their gums and gum treatment outcomes as well as to investigate the rol...

Detailed Description

Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by hyperandrogenism, polycystic ovaries, and ovulatory dysfunction, affecting 4-21 % of women worldwide. It has been shown that ...

Eligibility Criteria

Inclusion

  • Women aged 18-40 with polycystic ovary syndrome and healthy periodontium
  • Women aged 18-40 with polycystic ovary syndrome and gingivitis
  • Women aged 18-40 who are systemically healthy and have gingivitis
  • Women aged 18-40 who are systemically healthy and have a healthy periodontium
  • Presence of at least 20 permanent teeth

Exclusion

  • Receiving anti-inflammatory or antimicrobial therapy in the past three months
  • Smoking and alcohol consumption
  • Body mass index \> 30 kg/m2
  • Individuals with diabetes mellitus, hyperprolactinemia, congenital adrenal hyperplasia, androgen-secreting tumors, thyroid disorders, Cushing's syndrome, hypertension, liver or kidney dysfunction
  • Medication that may affect metabolic criteria, such as oral contraceptive agents, any steroid hormone or related preparations, hypertensive drugs and insulin sensitizing drugs
  • Pregnancy and breastfeeding
  • Receiving periodontal treatment in the last 6 months
  • Taking any medication known to affect periodontal status (e.g. phenytoin, calcium antagonists, cyclosporine, coumadin, steroidal non-anti-inflammatory drugs, aspirin \> 81 mg)
  • Active infectious diseases such as hepatitis, HIV or tuberculosis

Key Trial Info

Start Date :

March 15 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 8 2023

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT06567132

Start Date

March 15 2022

End Date

February 8 2023

Last Update

August 22 2024

Active Locations (1)

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Bezmialem University

Istanbul, Fatih, Turkey (Türkiye), 34080