Status:

RECRUITING

Retrospective Analysis of the Effect of In-hospital Initiation of PCSK9i on Clinical Outcomes in Chinese ACS Patients

Lead Sponsor:

Yun Dai Chen

Collaborating Sponsors:

Sanofi

Conditions:

Acute Coronary Syndrome

Eligibility:

All Genders

18+ years

Brief Summary

The objective of this study is to investigate the effectiveness of in-hospital initiation of alirocumab combined with statin ± ezetimibe on major cardiovascular events (MACE) in Chinese ACS patients. ...

Eligibility Criteria

Inclusion

  • Patients diagnosed with Acute Coronary Syndrome (ACS) upon hospital admission.
  • Patients aged 18 years or older.
  • Patients who received Alirocumab 75 mg in combination with statin therapy ± Ezetimibe as the intervention group, and those treated exclusively with statin therapy ± Ezetimibe as the control group, either during hospitalization or at discharge.
  • Patients with at least one follow-up record.

Exclusion

  • Patients who received Evolocumab treatment at any time.
  • Patients who received Inclisiran treatment at any time.

Key Trial Info

Start Date :

August 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 31 2025

Estimated Enrollment :

10000 Patients enrolled

Trial Details

Trial ID

NCT06567418

Start Date

August 1 2024

End Date

January 31 2025

Last Update

August 22 2024

Active Locations (1)

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1

Chinese PLA General Hospital

Beijing, Beijing Municipality, China, 100853