Status:

RECRUITING

Evaluation of Dentin Graft and I-PRF With and Without Vitamin C for Post-extraction Socket Preservation

Lead Sponsor:

Cairo University

Conditions:

Socket Preservation

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

The aim of the study is to evaluate radiographic ridge width change following autogenous demineralized dentin graft (ADDG) and i-PRF addition with and without vitamin C (AA) for post extraction socket...

Detailed Description

Research objective: Socket preservation is one of the techniques utilized to maintain bone dimension and minimized post-extraction dimensional changes. Adding vitamin C to dentin graft and i-PRF migh...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • ≥ 18 years of age.
  • Single extraction of non-molar teeth with periodontally healthy adjacent teeth.
  • Non-contributory medial history.
  • Non- restorable teeth indicated for extraction.
  • Requiring alveolar preservation after tooth extraction prior to placement of dental implant.
  • Participants that are eligible for immediate implantation, yet having factors that are hindering these patients from immediate placement of an implant at the time of extraction (ex: Financial related factors - psychological psychological factors - time related factors).
  • Cooperative patients who are willing to commit for 3 months follow up.

Exclusion

  • Pregnant female.
  • Acute infection at extraction site.
  • Systemic conditions affecting healing (e.g., diabetes, medications as bisphosphonates...)
  • A participant who had radiotherapy or chemotherapy.
  • Psychiatric patient, or with a learning disability, or unable to give consent.

Key Trial Info

Start Date :

November 4 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 28 2026

Estimated Enrollment :

26 Patients enrolled

Trial Details

Trial ID

NCT06569264

Start Date

November 4 2025

End Date

February 28 2026

Last Update

December 1 2025

Active Locations (1)

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1

Faculty of Dentistry, Cairo University

Cairo, Egypt