Status:

RECRUITING

A Study to Explore the Effect of SP-624 on Brain Network Analytics in Healthy Adults and Adults With Major Depression

Lead Sponsor:

Sirtsei Pharmaceuticals, Inc.

Conditions:

Major Depressive Disorder

Depression

Eligibility:

All Genders

18-60 years

Phase:

PHASE1

Brief Summary

The main goal of this clinical trial is to learn if the active study drug (code name: SP-624) has any effect on the electrical activity of the brain in adult healthy volunteers and in adults with majo...

Eligibility Criteria

Inclusion

  • Key
  • In generally good health
  • Body mass index (BMI) between 18.0 and 40.0 kg/m2
  • Willing to comply with the requirements of the study
  • For participants with depression: must meet study criteria for moderate to severe major depressive disorder
  • Key

Exclusion

  • Female who is pregnant or breastfeeding.
  • Clinically significant health condition or clinically significant abnormal results on screening health tests
  • For participants with depression: presence of exclusionary study criteria for co-morbid psychiatric conditions or medication history.

Key Trial Info

Start Date :

August 22 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2026

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT06570369

Start Date

August 22 2024

End Date

February 1 2026

Last Update

December 30 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

CenExel CNS

Garden Grove, California, United States, 92845

2

Alivation Research

Lincoln, Nebraska, United States, 68526