Status:
RECRUITING
DYNAMic Renal Assessment: NOvel Methods to Assess KIDNEY Functional Reserve
Lead Sponsor:
King's College Hospital NHS Trust
Collaborating Sponsors:
King's College London
Conditions:
Chronic Kidney Diseases
Eligibility:
All Genders
40+ years
Brief Summary
This is a feasibility study to assess new, more practical ways of measuring renal reserve.
Detailed Description
Quantification of glomerular filtration rate (GFR) over time is the standard assessment of kidney function. In clinical practice, the endogenous marker, 'serum creatinine' concentration, is used as a ...
Eligibility Criteria
Inclusion
- Inclusion:
- Patients with sickle cell nephropathy, diagnosed clinically or histologically. Sickle Cell patients will be confirmed Hb SS and eGFR (CKD-EPI) ≥ 135 ml/min/1.73m2 OR Previous living kidney donation Age ≥ 4No contraindication or known allergy to any trial medications. Willing and able to provide written informed consent
- Exclusion:
- Aged \< 40 Unable or unwilling to provide informed consent Breastfeeding or pregnant women Patients involved in other interventional research studies.
Exclusion
Key Trial Info
Start Date :
December 14 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2025
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT06572215
Start Date
December 14 2023
End Date
January 1 2025
Last Update
August 27 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
King's College Hospital
London, United Kingdom