Status:
RECRUITING
Quality of Labour Epidural Analgesia With Intrathecal Morphine as a Component of Combined Spinal Epidural
Lead Sponsor:
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Conditions:
Labor Pain
Eligibility:
FEMALE
18-50 years
Phase:
NA
Brief Summary
Neuraxial analgesia has shown to be the gold standard for effective labor pain relief, offering numerous benefits including enhanced pain control and maternal satisfaction. The methods to achieve neur...
Detailed Description
The addition of morphine to a combination of bupivacaine and lipophilic opioids (fentanyl) for the spinal component of CSE for labor analgesia has been shown to increase the duration of analgesia. A m...
Eligibility Criteria
Inclusion
- Adult (≥18 years) term primiparous (≥37 weeks) patients with live singleton pregnancy
- Patients who request labour analgesia and do not have any contraindications for neuraxial analgesia.
- Less than or equal to 6 cm cervical dilation during the last vaginal examination.
Exclusion
- Patients who are expected to be discharged within 24 hours of delivery.
- Patients with chronic pain conditions, opioid use disorder, pre-gestational diabetes, obstructive sleep apnea, morbid obesity (BMI \>40 kg/m2), or fetal abnormalities.
- Patients who have intramuscular morphine within 12 hours or fentanyl \>200 mcg in the preceding 4 hours.
- Participants will be excluded from further analysis in case of spinal analgesic failure
- Participants will be excluded from further analysis if labour lasts less than 2 hours
Key Trial Info
Start Date :
November 20 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2025
Estimated Enrollment :
182 Patients enrolled
Trial Details
Trial ID
NCT06572241
Start Date
November 20 2024
End Date
September 1 2025
Last Update
November 29 2024
Active Locations (1)
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1
Mount Sinai Hospital
Toronto, Ontario, Canada, M5G1X5