Status:

COMPLETED

Liver Status and Presence of MASLD/MASH in Patients With Chronic Hepatitis B

Lead Sponsor:

Yaşar Bayındır, MD

Collaborating Sponsors:

Nobel Pharmaceuticals

Conditions:

Chronic Hepatitis B

Hepatic Steatosis

Eligibility:

All Genders

18-65 years

Brief Summary

The aim of the study was to evaluate the consistency between liver biopsy and Liver Stiffness Measurement (LSM) for fibrosis and controlled attenuation parameter (CAP) for steatosis in FibroScan® in p...

Detailed Description

Patients aged 18 years and older with HBsAg positivity for more than six months and HBV-DNA level \>2,000 IU/ml were included in the study. The exclusion criteria were established as presence of cirrh...

Eligibility Criteria

Inclusion

  • Patients aged 18 years and older with HBsAg positivity for more than six months
  • Patients have HBV-DNA level \>2,000 IU/ml for more than six months

Exclusion

  • Presence of cirrhosis
  • Alcohol consumption \>140 g/week in women and 210 g/week in men
  • Hepatitis C coinfection
  • Hepatitis D and/or HIV coinfections

Key Trial Info

Start Date :

January 2 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 15 2024

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT06573190

Start Date

January 2 2023

End Date

May 15 2024

Last Update

August 27 2024

Active Locations (1)

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1

Guven Hospital

Ankara, Turkey (Türkiye), TR-06540