Status:

RECRUITING

Effect of 12-week Milk Fat Globule Membrane Supplementation on the Human Muscle Function of Healthy, Recreationally Active Adults

Lead Sponsor:

Loughborough University

Collaborating Sponsors:

Volac International Limited

Conditions:

Ageing Well

Neuromuscular Function

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

The main aim of this study is to understand if chronic supplementation (12 weeks) of a milk fat globule membrane containing supplement, called bioactive whey protein concentrate, improves human muscle...

Detailed Description

Nutritional strategies, including supplementation, are widely sought after to improve the function of the neuromuscular system (muscle strength and power). Milk fat globule membrane (MFGM, composed of...

Eligibility Criteria

Inclusion

  • 18-30 or 60-75 years old
  • Male or female
  • Healthy with no contraindications to exercise
  • Classified as recreationally active (meet the government's guidelines for weekly physical activity - 150 minutes of moderate physical activity or 75 minutes of vigorous physical activity)

Exclusion

  • Any injury, medical condition or symptom precluding the ability to complete strenuous exercise as identified by the health screen questionnaire and physical activity readiness questionnaire
  • Uncontrolled hypertension (blood pressure of 140/90 mmHg or higher) as identified by recording resting blood pressure
  • Neuromuscular or musculoskeletal disease
  • Occurrence of a severe injury to the lower limbs or back within the previous 6 months (time loss of \> 21 days of normal activity)
  • Occurrence of a minor injury to the lower limbs or back within the previous month (time loss of \>1 day of normal activity)
  • Do not meet the government guidelines of minimum weekly physical activity as revealed by the IPAQ-SF
  • Allergic to dairy or pea, or lactose intolerant
  • Complete greater than 6 hours structured exercise per week as revealed by the exercise and physical activity form
  • Consumption of supplements that may confound the results of the present study within the previous 3 months (includes any form of protein supplement, creatine, pre-workout supplements, any form of testosterone supplement, amino acids, beta-alanine, beta- hydroxy-beta-methylbutyrate (HMB), fish or krill oil, collagen supplements, any choline- containing supplement, or any phospholipid-containing supplement) as highlighted by the health screen questionnaire
  • Taking anticoagulants or antiplatelet drugs
  • Use of antidepressant/anti-anxiety medication
  • Having a blood borne virus, or a partner who has a blood-borne virus
  • Extreme diet classified as identified by the food-frequency questionnaire

Key Trial Info

Start Date :

March 28 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2026

Estimated Enrollment :

96 Patients enrolled

Trial Details

Trial ID

NCT06573749

Start Date

March 28 2025

End Date

January 1 2026

Last Update

April 2 2025

Active Locations (1)

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Loughborough University

Loughborough, Leicestershire, United Kingdom, LE11 3TU

Effect of 12-week Milk Fat Globule Membrane Supplementation on the Human Muscle Function of Healthy, Recreationally Active Adults | DecenTrialz