Status:
COMPLETED
Comparison of the Effects of Dexmedetomidine and Lidocaine on Blood Pressure and Heart Rate Response
Lead Sponsor:
Universitas Padjadjaran
Conditions:
General Anesthesia
Eligibility:
All Genders
18-59 years
Phase:
NA
Brief Summary
Endotracheal intubation is considered a definitive therapy and the gold standard for airway management. However, this procedure carries several risks, including sudden increases in blood pressure and ...
Detailed Description
Dexmedetomidine works very selectively on noradrenergic receptors distributed both within and outside the central nervous system, particularly in the pons and medulla. Presynaptic stimulation of α2 re...
Eligibility Criteria
Inclusion
- Patients aged 18-59 years.
- Patients scheduled for oral intubation.
- Physical status ASA I and II (American Society of Anesthesiologists).
- Patients with Mallampati classification I-II.
Exclusion
- History of allergy to the drugs that will be used.
- Pregnant patients.
- Patients taking medications that affect blood pressure and heart rate, such as vasodilators, adrenergic blockers, antiarrhythmics, and cardiac stimulants.
- Patients with arrhythmias, AV block, liver disorders, hypertension, and hypoalbuminemia.
- Patients who have been given opioids within the last 24 hours.
- Patients with predicted intubation difficulties.
Key Trial Info
Start Date :
May 29 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 14 2024
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT06573957
Start Date
May 29 2024
End Date
August 14 2024
Last Update
August 27 2024
Active Locations (1)
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1
RSUP Dr. Hasan Sadikin
Bandung, West Java, Indonesia, 40161