Status:
RECRUITING
Dexmedetomidine Reduces Sevoflurane MAC-BAR During Pneumoperitoneum
Lead Sponsor:
Fujian Provincial Hospital
Conditions:
Laparoscopic Cholecystectomy
Eligibility:
All Genders
18-45 years
Phase:
PHASE4
Brief Summary
This clinical trial aims to learn the impact of dexmedetomidine on the minimum alveolar concentration blunting the adrenergic response (MAC-BAR) of sevoflurane to carbon dioxide pneumoperitoneum in pa...
Detailed Description
Laparoscopic (minimally invasive) surgery has several advantages over open surgery, including less tissue damage, faster recovery, and fewer complications. This has led to widespread use of laparoscop...
Eligibility Criteria
Inclusion
- 1\. Aged 18-45 years.
- 2\. American Society of Anesthesiologists (ASA) grade I - II.
- 3\. Patients undergoing elective laparoscopic cholecystectomy.
Exclusion
- 1\. Inability to provide informed consent;
- 2\. History of chronic pain or substance abuse;
- 3\. Pregnancy;
- 4\. Body mass index (BMI) ≥ 30 kg/m2;
- 5\. Known allergies to the study medications;
- 6\. Intake of medications within the last 72 hours that potential interfere with the determination of the MAC-BAR;
- 7\. Any other condition deemed exclusionary by the investigators.
Key Trial Info
Start Date :
September 2 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2024
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT06575179
Start Date
September 2 2024
End Date
December 30 2024
Last Update
October 1 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Fujian Provincial Hospital
Fuzhou, Fujian, China, 350001