Status:

RECRUITING

Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Pain, Anxiety and Depression in Patients With Resectable Head and Neck Squamous Cell Carcinoma

Lead Sponsor:

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Conditions:

Head and Neck Squamous Cell Carcinoma

Eligibility:

All Genders

18-80 years

Brief Summary

The goal of this observational study is to learn about the Effects of neoadjuvant therapy with carboplatin, paclitaxel combined with anti-PD-1 drugs on pain, anxiety and depression in patients with op...

Eligibility Criteria

Inclusion

  • \- 1: Clinical diagnosis of head and neck squamous cell carcinoma (stage I-IVA), without prior treatment, and planning to undergo either surgical treatment alone or surgical treatment combined with chemotherapy and immunotherapy.
  • 2: Ability to speak Chinese and possess basic reading and writing skills.

Exclusion

  • 1: Presence of mental illnesses such as dementia or delirium.
  • 2: Active use of narcotic drugs, including consuming alcohol more than 4 times per day or more than 4 times per week.
  • 3: Patients who alter their treatment plan during the course of treatment.
  • 4: Current or prior use of antidepressants.

Key Trial Info

Start Date :

September 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2027

Estimated Enrollment :

302 Patients enrolled

Trial Details

Trial ID

NCT06575322

Start Date

September 1 2024

End Date

March 1 2027

Last Update

August 28 2024

Active Locations (1)

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Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Guanzhou, Guangdong, China, 510000