Status:

RECRUITING

Using Simplified Meal Boluses Versus Carbohydrate Counting in Adolescents With Hybrid Closed Loop Systems

Lead Sponsor:

University of Colorado, Denver

Conditions:

Type 1 Diabetes

Eligibility:

All Genders

14-26 years

Phase:

NA

Brief Summary

The goal of this trial is to evaluate blood sugar control in patients with type 1 diabetes when using a simple meal bolus strategy (small, medium, large meals) compared to carbohydrate counting when o...

Detailed Description

This is a prospective randomized crossover trial in adolescents and adults on HCL systems at the Barbara Davis Center for Childhood Diabetes (BDC) with the objective of testing a new simple meal bolus...

Eligibility Criteria

Inclusion

  • Clinical diagnosis of T1D of at least 1 year duration
  • Using a commercial HCL system
  • Willingness to not start any new non-insulin glucose-lowering agent during trial
  • Willingness to participate in all study procedures
  • Investigator has confidence that participant can successfully operate all study devices and adhere to protocol

Exclusion

  • History of \>1 severe hypoglycemic event with seizure or loss of consciousness in the last 6 months or \>1 DKA event in the last 6 months not related to illness or infusion set failure
  • History of chronic renal disease or currently on hemodialysis, adrenal insufficiency, hypothyroidism that is not adequately treated, use of oral or injectable steroids within the last 8 weeks, or known ongoing adhesive intolerance
  • A condition, which in the opinion of the investigator or designee, would put the participant or study at risk
  • Participation in another interventional trial at the time of enrollment
  • Pregnancy

Key Trial Info

Start Date :

November 25 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 30 2025

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06575790

Start Date

November 25 2024

End Date

September 30 2025

Last Update

December 10 2024

Active Locations (1)

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Barbara Davis Center

Aurora, Colorado, United States, 80045