Status:
RECRUITING
Thailand HIV and Stigma Reduction Study
Lead Sponsor:
University of Massachusetts, Worcester
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Institute of HIV Research and Innovation Foundation, Thailand
Conditions:
Pre-Exposure Prophylaxis
Eligibility:
MALE
18-29 years
Phase:
NA
Brief Summary
This project will develop a multi-component, technology-delivered intervention designed to reduce HIV and intersectional stigma and improve the use of HIV pre-exposure prophylaxis (PrEP) among HIV-neg...
Eligibility Criteria
Inclusion
- Aim 1 (Formative Research and Beta-Testing) Transgender women
- Ages between 18 and 29 years
- Male sex at birth
- Self-identifies as women, transgender women or culturally identifies with the female spectrum
- Laboratory-confirmed HIV-negative status
- Self-reported recent history of condomless sex
- Able to understand, read and speak Thai
- Either not started PrEP or currently on PrEP but not adherent (taking ≤3 pills/week) in the past month.
Exclusion
- Have a serious cognitive or psychiatric problem compromising ability to provide informed consent
- Have active suicidal ideation or major mental illness at the time of interview (these patients will be referred for treatment)
- Laboratory or clinical findings that would preclude PrEP initiation (e.g., decreased creatinine clearance)
- Currently enrolled in another HIV intervention study.
- Healthcare providers Inclusion criteria
- Age 18 or above
- Has provided HIV prevention or treatment services for TGW for at least one year Exclusion criteria
- None
- Aim 2 (Pilot RCT) Transgender women Inclusion criteria
- Ages between 18 and 29 years
- Male sex at birth
- Self-identifies as women, transgender women or culturally identifies with the female spectrum
- Laboratory-confirmed HIV-negative status
- Self-reported recent history of condomless sex
- Able to understand, read and speak Thai
- Either not started PrEP or currently on PrEP but not adherent (taking ≤3 pills/week) in the past month.
- Exclusion criteria
- Have a serious cognitive or psychiatric problem compromising ability to provide informed consent
- Have active suicidal ideation or major mental illness at the time of interview (these patients will be referred for treatment)
- Laboratory or clinical findings that would preclude PrEP initiation (e.g., decreased creatinine clearance)
- Currently enrolled in another HIV intervention study.
Key Trial Info
Start Date :
February 20 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 14 2027
Estimated Enrollment :
154 Patients enrolled
Trial Details
Trial ID
NCT06576648
Start Date
February 20 2025
End Date
August 14 2027
Last Update
September 8 2025
Active Locations (3)
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1
Institute of HIV Research and Innovation
Bangkok, Thailand
2
Rainbow Sky Association of Thailand
Bangkok, Thailand
3
SWING Foundation
Bangkok, Thailand