Status:
COMPLETED
Satiety and Alcohol Challenge
Lead Sponsor:
University of North Carolina, Chapel Hill
Collaborating Sponsors:
Research Society on Alcohol
North Carolina Translational and Clinical Sciences Institute
Conditions:
Alcohol Drinking
Eligibility:
All Genders
21-45 years
Phase:
NA
Brief Summary
The goal of this pilot study is to identify the role of satiety on responses to alcohol drinking using human subject laboratory methods. Satiety will be manipulated over two sessions using a dietary s...
Detailed Description
Participants will receive a beverage containing either a dietary supplement (10g Fibersol®-2 mixed with water and aspartame sweetener for taste + 725mg decaffeinated green tea extract capsule) or a ca...
Eligibility Criteria
Inclusion
- Age 21-45
- Meeting NIAAA criteria for current at-risk drinking (i.e., \>7/14 drinks in one week for women/men, with at least one episodes of 4+/5+ drinks in the past 30 days)
- Willingness to complete laboratory sessions involving blood draws and alcohol administration
- Ability to communicate and read in English
- Body mass index (BMI) of 21 - 30 kg/m\^2
Exclusion
- Meets past-year criteria for severe Alcohol Use Disorder (\>7 of 11 symptoms endorsed) or AUDIT score of 20+
- Meeting past-year criteria for a substance use disorder (with the exception of alcohol, tobacco or mild cannabis use disorder)
- Current engagement in alcohol treatments, or currently engaged in intentional efforts to quit alcohol use
- Current use of weight control medications
- Lifetime diagnosis of severe mental illness (including schizophrenia and bipolar disorder)
- History of suicide attempt, or psychiatric hospitalization in the last 6 months
- History of diabetes
- Medical conditions or medications for which alcohol is contraindicated
- Pregnant, nursing, or trying to become pregnant
- Plans to travel during the duration of study participation
Key Trial Info
Start Date :
September 3 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 9 2025
Estimated Enrollment :
64 Patients enrolled
Trial Details
Trial ID
NCT06576674
Start Date
September 3 2024
End Date
April 9 2025
Last Update
December 5 2025
Active Locations (1)
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1
University of North Carolina
Chapel Hill, North Carolina, United States, 27599