Status:
RECRUITING
Effect of Procyanidins in Leaky Gut Repairing in IBD
Lead Sponsor:
University of Padova
Conditions:
Ulcerative Colitis in Remission
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to learn if the Grape Seed Extract Ecovitis, featuring low monomeric catechins content and a high concentration of oligo-polymeric procyanidins, could modulate the G...
Detailed Description
The leaky gut is an alteration of the intestinal epithelium capable of compromising the functionality of the intestinal barrier, permitting the entry of foods or viral/bacterial proteins, and then sti...
Eligibility Criteria
Inclusion
- Diagnosis of UC confirmed by clinical, endoscopic and histopathological evidence. Disease in remission phase confirmed by clinical, endoscopic and histopathological evidence.
- Age between 18 and 75 years old
- Ability of subject to participate fully in all aspects of this clinical trial.
Exclusion
- ● Patients that have active UC, determined by clinical, endoscopic and histopathological evidences
- Known diagnosis of CD, indeterminate colitis, ischemic colitis, radiation colitis, diverticular disease associated with colitis or microscopic colitis
- Positive stool culture for active C. difficile
- Pregnant women
- Patients under antibiotic and/or probiotic treatment within 10 days prior to Visit 1.
Key Trial Info
Start Date :
June 15 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 12 2026
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT06576700
Start Date
June 15 2024
End Date
June 12 2026
Last Update
September 19 2024
Active Locations (1)
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1
Edoardo Vincenzo Savarino
Padua, Padua, Italy, 35128