Status:

RECRUITING

The Effect Of Botox In Patients With Gummy Smile With And Without Zinc And Phytase Supplementation.

Lead Sponsor:

Cairo University

Conditions:

Excessive Gingival Display

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

Participants with esthetic concern of excessive gingival display who meets the inclusion criteria, will be carried out including history taking, clinical examination and initial therapy. The initial ...

Detailed Description

Initial examination: Participants with esthetic concern of excessive gingival display who meets the inclusion criteria, will be carried out including history taking, clinical examination and initial ...

Eligibility Criteria

Inclusion

  • Patients with excessive gingival display \>3mm and with normal clinical crown dimensions.
  • Adults \>18 years.
  • Non-smokers.
  • Systemically healthy.
  • Hypermobile lip and mild VME.

Exclusion

  • Severe VME.
  • Pregnant or lactating females.
  • Patients with inflamed gingiva or gingival enlargement.
  • Inflammation or infection at the site of injection.
  • Patients with known allergy to any of the components of BTX-A or BTX-B (i.e. BTX, human albumin, saline, lactose and sodium succinate).
  • Patients using anticholinesterase or other agents interfering with neuromuscular transmission.
  • Psychologically unstable or who have questionable motives and unrealistic expectations.
  • Dependent on intact facial movements and expressions for their livelihood (e.g. actors, singers, musicians and other media personalities).
  • Afflicted with a neuromuscular disorder (e.g. myasthenia gravis, Eaton- Lambert syndrome).

Key Trial Info

Start Date :

June 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2025

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT06577285

Start Date

June 1 2024

End Date

June 1 2025

Last Update

September 23 2024

Active Locations (1)

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1

Faculty of Dentistry Cairo University

Cairo, Egypt