Status:
NOT_YET_RECRUITING
Use of Preoperative Sodium Bicarbonate Among Women With Obstructed Labor
Lead Sponsor:
Busitema University
Collaborating Sponsors:
University of Liverpool
Oslo University Hospital
Conditions:
Obstructed Labor
Eligibility:
FEMALE
16-49 years
Phase:
PHASE3
Brief Summary
The goal of this clinical trial is to determine a universal safe and effective dose of sodium bicarbonate for use among women with Obstructed labour to treat acidosis. It will also learn about the saf...
Detailed Description
Oral bicarbonate is a safe, cheap and effective acid buffer, widely used in sports to improve performance because of its ability to prevent and reverse the effects of metabolic acidosis. Clinically, i...
Eligibility Criteria
Inclusion
- Patients with obstructed labour
- Must be a singleton pregnancy
- Must be a term pregnancy (≥37 weeks of gestation)
- Must be in cephalic presentation.
Exclusion
- Patients with other obstetric emergencies such as antepartum haemorrhage, preeclampsia and eclampsia (defined as elevated blood pressure of at least 140/90 mm Hg, urine protein of at least 2+, any of the danger signs and fits), premature rupture of membranes and intrauterine fetal death.
- Patients with comorbidities such as diabetes mellitus, sickle cell disease, renal disease, liver disease and heart disease.
- Patients with hypokalaemia (148 mmol/L) and alkalosis (bicarbonate \>22 mmol/L) because they are more likely to develop adverse drug reactions
Key Trial Info
Start Date :
September 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2025
Estimated Enrollment :
280 Patients enrolled
Trial Details
Trial ID
NCT06579690
Start Date
September 1 2024
End Date
June 30 2025
Last Update
September 4 2024
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