Status:
RECRUITING
Exploring the Effects of Exercise on Memory and Cognition in Parkinson´s Disease
Lead Sponsor:
Heidelberg University
Collaborating Sponsors:
German Foundation for Neurology
University Hospital Heidelberg
Conditions:
Parkinson Disease
Eligibility:
All Genders
50-80 years
Phase:
NA
Brief Summary
The study aims to assess the effects of cardiovascular (aerobic) training on memory formation and cognitive function in people with Parkinson's disease. Participants will be randomly allocated to one ...
Detailed Description
Besides the disabling cardinal motor symptoms, non-motor symptoms are a common clinical feature of Parkinson's disease (PD). These non-motor symptoms include, amongst others, cognitive decline and mem...
Eligibility Criteria
Inclusion
- Diagnosed Parkinson's disease
- Disease stage ≤3 on the Hoehn \& Yahr scale
- Age ranging from 50 - 80 years
- Naive to the memory tasks (primary outcomes)
- Ability to stand and walk at least 10 meters independently
Exclusion
- Atypical Parkinsonism
- Significant level of cognitive impairment (i.e., Montreal Cognitive Assessment \<21)
- Deep brain stimulation or brain pacemaker
- Diagnosed psychiatric illness
- Known clinically relevant neurological, internal or orthopedic conditions besides Parkinsonism that would interfere with the exercise paradigm
- Exceeding the recommended level of cardiovascular exercise for older adults (i.e., cardiovascular exercise done ≥150 min per week of moderate-intensity or ≥75 min per week of vigorous-intensity)
Key Trial Info
Start Date :
February 27 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2027
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06580977
Start Date
February 27 2024
End Date
July 1 2027
Last Update
August 30 2024
Active Locations (1)
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1
Heidelberg University
Heidelberg, Baden-Wurttemberg, Germany, 69120