Status:

RECRUITING

Normalizing Antibody Detection in First-void Urine

Lead Sponsor:

Universiteit Antwerpen

Collaborating Sponsors:

University Hospital, Antwerp

Conditions:

Human Papillomavirus Infection

Eligibility:

All Genders

9-70 years

Brief Summary

The aim of this study is to develop robust analytical protocols for the monitoring of vaccine induced immunity against the Human Papillomavirus (HPV) in first-void urine samples and to examine fluctua...

Detailed Description

To date, invasive clinician-collected cervical samples, blood, and vaginal samples are still the primary methods to monitor disease and immune responses to vaccine-preventable genital tract infections...

Eligibility Criteria

Inclusion

  • Vaccinated with either the Cervarix, Gardasil or Gardasil9 HPV-vaccine and able to present vaccination booklet or another official document proving this.
  • Able to understand the information brochure and what the study is about.
  • Willing to give informed consent to contact his/her general practitioner and/or gynecologist to access details on their HPV vaccination schedule and, in case a woman within the screening population, cervical cancer screening results (smears, HPV tests, colposcopy, biopsy).

Exclusion

  • Participating in another clinical trial at the same time of participating in this study.
  • Women that underwent hysterectomy or were treated for cervical (pre)cancer lesions within the six months prior to study enrolment.
  • Pregnant women.
  • Being positive for Human Immunodeficiency Virus (HIV), Hepatitis B or Hepatitis C.
  • Having a history or current evidence of any condition or abnormality that might confound the results of the study or is not in the best interest of the individual to participate, in the opinion of the investigator.

Key Trial Info

Start Date :

December 7 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2026

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT06582654

Start Date

December 7 2023

End Date

January 1 2026

Last Update

September 3 2024

Active Locations (1)

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1

University of Antwerp

Edegem, Antwerp, Belgium, 2650