Status:

RECRUITING

Black Rice Consumption on Cognitive Function, Inflammation and Microvascular Function in Older Adults

Lead Sponsor:

University of Reading

Conditions:

Older Adults

Eligibility:

All Genders

50-80 years

Phase:

NA

Brief Summary

Cognitive (brain) function, especially memory, gradually declines during ageing, which may in part be caused by an increase in systemic inflammation as well as a reduction in vascular functions and ce...

Detailed Description

This study is a randomised controlled crossover design with a week wash-out period for investigating the acute (2 hrs), short-term (7 days), and acute on short-term (7 days, 2 hrs) effects of black ri...

Eligibility Criteria

Inclusion Criteria:

  • Aged 50-80 years
  • General healthy status
  • Body Mass Index (BMI)18.5-35 kg/m2

Exclusion Criteria:

  • Taking anti-inflammatory drugs (e.g., aspirin, warfarin, ibuprofen)
  • Having sign of infections or acute inflammation (e.g., fever, chills, sore throat, nasal congestion, moderate-severe pain, swelling-redness)
  • Received antibiotics within the past 3 months
  • Taking dietary supplements (e.g., vitamins, minerals) at high doses (e.g., more than 200% of the UK's reference nutrient intakes)
  • Taking hormone replacement therapy, if you are menopausal
  • Had major surgery (head, heart, chest, abdomen) within the past 6 months.
  • Having plan to start to a restricted diet/ changing dietary pattern or lose weight.
  • Diagnosed with neurodegenerative diseases (e.g., Dementia, Alzheimer's, Parkinson's, current stroke)
  • Diagnosed with psychotic disorders (e.g., schizophrenia, bipolar depression, eating disorder)
  • Diagnosed with cardiovascular disease, diabetes, hyperlipidemia, hypertension (blood pressure>140/90 mmHg), active cancer, liver, or kidney diseases.
  • Taking medication to lower blood fats (e.g., statins, fibrates) or to stabilise blood glucose (e.g., acarbose, metformin or sulfonylureas) or lower blood pressure.
  • Unable to complete the cognitive function tasks for any reason (i.e., visual impairments, hearing loss)
  • If you have a peacemaker
  • If you have bleeding disorders or blood related diseases (anaemia, thalassemia, thrombosis, embolism)
  • Heavy smoker
  • Heavy alcohol drinking (> 14 units/week) or a history of alcohol/substance abuse
  • Allergies, hypersensitivity, or food intolerances (rice, eggs, soy sauce, vegetable oil)

Key Trial Info

Start Date :

December 5 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2024

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT06583785

Start Date

December 5 2023

End Date

December 31 2024

Last Update

September 4 2024

Active Locations (2)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (2 locations)

1

Hugh Sinclair Unit of Human Nutrition

Reading, UK, United Kingdom, RG2 6AP

2

Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading

Reading, United Kingdom, RG2 6AP

Black Rice Consumption on Cognitive Function, Inflammation and Microvascular Function in Older Adults | DecenTrialz