Status:

RECRUITING

Molecular Pituitary Imaging Using 18F-FET PET

Lead Sponsor:

University of Cambridge

Collaborating Sponsors:

Cambridge University Hospitals NHS Foundation Trust

Conditions:

Pituitary Adenoma

Eligibility:

All Genders

18-100 years

Phase:

NA

Brief Summary

The goal of this single centre pilot study is to explore whether 18F-fluoro-ethyl-tyrosine PET (FET-PET) yields comparable findings to 11C-methionine PET (Met-PET) for the localisation of pituitary tu...

Detailed Description

Up to 20 patients with pituitary adenomas (PA) who have previously undergone 11C-methionine PET (Met-PET) as part of routine clinical care will undergo 18F-fluoroethyltyrosine PET (FET-PET). Patients ...

Eligibility Criteria

Inclusion

  • Inclusion criteria
  • Participant is willing and able to give informed consent for participation in the study
  • Male or female, age 18 or above
  • Presence of pituitary adenoma suspected on the basis of clinical/biochemical and/or radiological findings
  • Previous 11C-Met-PET/CT
  • Exclusion criteria
  • Inability to give informed consent
  • Pregnancy or suspected pregnancy
  • Inability to lie supine for 30-60 minutes
  • Patient body habitus above scanner dimensions
  • Known allergy to intravenous radiographic contrast agents

Exclusion

    Key Trial Info

    Start Date :

    September 3 2024

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 31 2026

    Estimated Enrollment :

    20 Patients enrolled

    Trial Details

    Trial ID

    NCT06584123

    Start Date

    September 3 2024

    End Date

    December 31 2026

    Last Update

    January 6 2026

    Active Locations (1)

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    1

    Cambridge University Hospitals

    Cambridge, Cambridgeshire, United Kingdom, CB2 0QQ