Status:

UNKNOWN

Evaluation of Serum Gasdermin D Level As a Potential Biomarker of Disease Activity in Vitiligo Patients

Lead Sponsor:

Assiut University

Conditions:

Serum Gasdermin D in Vitiligo

Eligibility:

All Genders

10-75 years

Brief Summary

Assessment the serum level of Gasdermin D level in vitiligo patients. Correlate its level with disease activity scores using Vitiligo Area Severity Index (VASI) and Vitiligo Disease Activity (VIDA) sc...

Detailed Description

Vitiligo, a common depigmenting skin disorder, has an estimated prevalence of 0.5-2% of the population worldwide. The disease is characterized by the selective loss of melanocytes which results in typ...

Eligibility Criteria

Inclusion

  • All clinically diagnosed cases of vitiligo (segmental and non-segmental).

Exclusion

  • patients with inflammatory diseases.
  • patients with autoimmne diseases.
  • patients with neurodegenerative diseases.
  • patients with HIV or COVID19 infection or any other type of infections.
  • patients with systemic diseases as liver diseases or having tumors.
  • patients who received systemic treatment in the last 3 months or topical treatment 1 month prior to the study.

Key Trial Info

Start Date :

November 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

84 Patients enrolled

Trial Details

Trial ID

NCT06584643

Start Date

November 1 2024

End Date

December 1 2025

Last Update

September 5 2024

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