Status:

RECRUITING

High-flow Nasal Oxygen Therapy in Obese Patients Undergoing Sedative Gastroscopy

Lead Sponsor:

XiaoLiang Wang

Conditions:

Hypoxia

Obesity

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Obese patients often have fat accumulation in the head and neck, increased soft tissue in the oropharynx, decreased lung compliance, decreased lung volume and residual volume, and some obese patients ...

Detailed Description

Gastroscopy is a common method for screening and diagnosing digestive diseases, with approximately 23 million cases performed in China annually. However, this invasive procedure can cause patients to ...

Eligibility Criteria

Inclusion

  • Patients undergoing sedative gastroscopy
  • Aged over 18.
  • ASA classification I-III
  • Interincisal distance \>6.5cm, no micrognathia, limited mouth opening and limited cervical spine movement
  • Compliance with ethics, patient willing to participate in the trial, signed informed consent form

Exclusion

  • Contraindications for endoscopic procedures or patients refusing sedation/anesthesia.
  • Patients with allergies to propofol, eggs, soybeans, or milk.
  • Patients with gastrointestinal obstruction and gastric emptying disorders.
  • Patients with acute pharyngitis, tonsillitis, and upper respiratory tract infections.
  • 5: Patients with acute exacerbations of respiratory diseases such as asthma, bronchitis, and COPD. 6. Patients with acute arrhythmias and severe heart disease (congenital, valvular disease). 7. Patients requiring replacement therapy for severe liver or kidney dysfunction.
  • 8\. Patients with severe mental illnesses requiring medication to control symptoms.
  • 9\. Patients with moderate to severe anemia, coagulation disorders, and hematological diseases. 10. Patients with severe nasal congestion caused by nasal cavity lesions. 11. Pregnant and lactating patients.

Key Trial Info

Start Date :

October 23 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 20 2025

Estimated Enrollment :

864 Patients enrolled

Trial Details

Trial ID

NCT06585306

Start Date

October 23 2024

End Date

October 20 2025

Last Update

April 1 2025

Active Locations (1)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (1 locations)

1

Nanjing First Hospital

Nanjing, Jiangsu, China, 210006