Status:
COMPLETED
Outcome of Complete Pulpotomy in Healthy and Type 2 Diabetic Patients in Permanent Teeth with Irreversible Pulpitis
Lead Sponsor:
Postgraduate Institute of Dental Sciences Rohtak
Conditions:
Irreversible Pulpitis
Diabetes Mellitus, Type 2
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Endodontic research on the effects of DM on pulp tissues is scarce. Diabetic human and animal histological research demonstrated a decreased reparatory response in the pulp, resulting in chronic pulp ...
Detailed Description
Introduction: Endodontic disease can affect both the pulp and the periapical areas of the tooth. The resultant immune-pathological reaction could be acute or chronic inflammation, depending on the ab...
Eligibility Criteria
Inclusion
- Type 2 diabetes mellitus with HbA1c \> 6.5% with no other co-morbidities.
- Age and gender matched healthy patients
- Age between 18 - 70 years.
- Mature permanent teeth with clinical and radiographic signs and symptoms indicative of irreversible pulpitis (PAI score ≤2)
- Tooth showing positive response to pulp sensibility testing.
Exclusion
- Patients with immunocompromised diseases or systematic diseases (other than diabetes mellitus)
- Smokers, pregnant and lactating women
- Teeth with immature roots or retained deciduous tooth.
- Bleeding could not be controlled in ≥8 minutes.
- Tooth with signs and symptoms of apical periodontitis.
- Tooth with probing depth more than 4mm.
- Positive history of antibiotic use in the past 1 month or requiring antibiotic prophylaxis and/or analgesic usage in past 3 days.
Key Trial Info
Start Date :
August 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2024
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06586775
Start Date
August 1 2023
End Date
August 1 2024
Last Update
September 19 2024
Active Locations (1)
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1
Dr.keerthana
Rohtak, Haryana, India, 124001