Status:
COMPLETED
Nitrate Mouth Rinse and the Oral Microbiome
Lead Sponsor:
Dalhousie University
Conditions:
Nitric Oxide
Oral Microbiome
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
The study is aimed to determine if changes to the oral microbiome occur after the use of a nitrate rich mouth rinse. Participants with be asked to use either a controlled (water) mouthrinse once daily...
Detailed Description
Nitrate is found in high concentrations in beet root, and as such we will use a beet root based product as a daily mouth rinse (Swish and Spit) as a part of the participants daily oral hygiene regimen...
Eligibility Criteria
Inclusion
- You are between the ages of 18 and 40. Have no uncontrolled systemic diseases.
- Participants with mild chronic conditions such as:
- Asthma
- Type 1 Diabetes Mellitus
Exclusion
- You are under the age of 18.
- You have uncontrolled systemic diseases, or acute infections.
- You are taking prescription, antibiotics, probiotics, or antimicrobial mouthrinses.
- You have a documented true allergy (i.e Hives, Swelling of lips/throat) Soy, Nuts, Seeds, Dairy, Egg products, Fish/Shellfish or Wheat.
- The presence of acute or chronic oral conditions including:
- Herpes Simplex Virus (recent cold sores)
- Stomatitis
- Oral Lichen Planus
- Angular Cheilitis
- Candidiasis
- Necrotizing Gingival Diseases
- Other inflammatory or infectious pathologies
- Active dental caries "cavities"
- Any other periodontal diagnosis other than 'Healthy Periodontium' or localized gingivitis
Key Trial Info
Start Date :
August 14 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 16 2025
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT06588049
Start Date
August 14 2024
End Date
May 16 2025
Last Update
September 2 2025
Active Locations (1)
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1
Dalhousie University
Halifax, Nova Scotia, Canada, B3H4R2