Status:

COMPLETED

Correlation Between RISANKIZUMAB's Trough Levels, Clinical and Biological Remission in Moderate to Severe Crohn's Disease: a Retrospective Multicentric Study

Lead Sponsor:

Centre Hospitalier Universitaire de Nīmes

Conditions:

Inflammatory Bowel Diseases

Eligibility:

All Genders

18+ years

Brief Summary

The goal of this observational study is to determine if, as with other therapeutics such as anti-TNF, trough levels of Risankizumab are correlated with clinical and biological remission in patients wi...

Detailed Description

The treatment of chronic inflammatory bowel disease has undergone a number of therapeutic revolutions in recent years, with the emergence of new biotherapies. These include RISANKIZUMAB, an anti-IL23 ...

Eligibility Criteria

Inclusion

  • Age ≥18 years
  • Patients with moderate to severe Crohn's disease
  • Failure of at least one immunosuppressant and one anti-TNF alpha agent
  • Patients on Risankizumab
  • No opposition to study participation

Exclusion

  • Age \< 18 years
  • UC
  • Unclassified colitis
  • Risankizumab prescribed to prevent post-operative relapse
  • Any contraindication to Risankizumab
  • Refusal to participate in study

Key Trial Info

Start Date :

June 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 30 2024

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06589895

Start Date

June 1 2021

End Date

May 30 2024

Last Update

September 19 2024

Active Locations (1)

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Centre Hospitalier Universitaire de Nîmes

Nîmes, Gard, France, 30029