Status:
NOT_YET_RECRUITING
Perioperative Rehabilitation Therapy in Patients Undergoing Liver Transplantation
Lead Sponsor:
Zhejiang University
Conditions:
Liver Transplantation
Sarcopenia
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Patients undergoing liver transplantation frequently experience a reduction in skeletal muscle mass, malnutrition, and decreased levels of physical activity. These complications can adversely affect e...
Eligibility Criteria
Inclusion
- Age between 18 and 70 years.
- Patients with end-stage liver disease who meet the criteria for liver transplantation (for liver cancer cases, only recipients meeting specific standards are included).
- Complete clinical information, including documented pre-transplant muscle status (e.g., preoperative CT scans and handgrip strength tests).
- High compliance with treatment, fully capable of independent action or having at least one assistant.
- No contraindications to the planned interventions.
Exclusion
- Presence of musculoskeletal disorders before transplantation, such as myositis, idiopathic muscle atrophy, or history of hip surgery within the past three months.
- Coexisting severe cardiovascular or cerebrovascular diseases, infectious diseases, or epilepsy.
- Liver transplantation due to autoimmune liver disease or drug-induced liver failure.
- Re-transplantation, multi-organ transplantation, living donor liver transplantation, split liver transplantation, or pediatric liver transplantation.
- ABO-incompatible liver transplantation.
- Incomplete clinical information.
- Difficulty in follow-up.
Key Trial Info
Start Date :
October 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
750 Patients enrolled
Trial Details
Trial ID
NCT06591507
Start Date
October 1 2024
End Date
December 31 2027
Last Update
September 19 2024
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