Status:

ACTIVE_NOT_RECRUITING

The LvL UP Trial: Assessing the Effectiveness of a MHealth Intervention

Lead Sponsor:

Singapore ETH Centre

Collaborating Sponsors:

ETH Zurich

National University of Singapore

Conditions:

Health Behavior

Noncommunicable Diseases

Eligibility:

All Genders

21-59 years

Phase:

NA

Brief Summary

Non-communicable diseases (NCDs), such as cardiovascular disease, diabetes, or cancer, and common mental disorders (CMDs), such as depression or anxiety, represent the primary causes of death and disa...

Detailed Description

Participants will: * Visit the study site at baseline and month 6 to complete assessments. * Complete online assessments at months 1, 3, 9 and 12. * Be assigned to group 1 (intervention) or group 2 (...

Eligibility Criteria

Inclusion

  • (i) aged 21 to 59 years,
  • (ii) Singapore citizens, permanent residents, or foreigners residing in Singapore on long-term passes with at least 1 year of validity remaining,
  • (iii) planning to reside in Singapore for the duration of the study (eligible participants can undertake sporadic trips overseas, as long as these do not conflict with in-person study visits),
  • (iv) proficient in English (the LvL UP app is currently only available in English),
  • (v) owners of a smartphone (minimum requirements: iOS version 12.4 and Android version 8) with internet access,
  • (vi) able to provide informed consent, and
  • (vii) identified as 'at risk' of developing non-communicable diseases and/or common mental disorders.

Exclusion

  • (i) diagnosed with one of the following chronic diseases: heart disease (e.g., heart attack and stroke), cancer, chronic respiratory diseases (e.g., chronic obstructed pulmonary disease and asthma), diabetes (type 1 or type 2), or chronic kidney disease.
  • (ii) diagnosed with one of the following mental disorders: major depressive disorders (depression), bipolar, eating disorders, post-traumatic stress disorder (PTSD), anxiety disorders, severe personality disorder, substance use disorders, or other mental health conditions diagnosed by a mental health professional.
  • (iii) pregnant, (iv) currently taking medications prescribed for high blood pressure or high blood glucose.
  • (v) past or current LvL UP users, including participants from the LvL UP pilot trial (NCT06360029) or HAPPY trial (Harnessing Human Potential and Improving Health Span in Women and their Children Trial).
  • (vi) already participating or planning to participate in the LvL UP trial as a 'LvL UP Buddy\'.
  • (vii) enrolled or planning to enroll in another lifestyle intervention research study before or during the study period.

Key Trial Info

Start Date :

October 21 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2026

Estimated Enrollment :

1073 Patients enrolled

Trial Details

Trial ID

NCT06592443

Start Date

October 21 2024

End Date

February 1 2026

Last Update

February 19 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Saw Swee Hock School of Public Health

Singapore, Singapore, 117549

2

Singapore ETH Center

Singapore, Singapore, 138602