Status:
COMPLETED
Intravenous Metoprolol in Septic Shock
Lead Sponsor:
Alexandria University
Conditions:
Septic Shock
Ventilator Acquired Pneumonia
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
A RCT designed to assess the effect of giving intravenous beta-blockers in patients with septic shock after achieving hemodynamic stability. The principle of this study is to control heart rate allowi...
Detailed Description
A RCT, conducted at alexandria main university hospital, patients were divided into 2 groups, Control group which received the standard care for septic shock and metoprolol group which recieved intrav...
Eligibility Criteria
Inclusion
- The study population included adult patients (≥ 18 years) diagnosed with septic shock secondary to VAP with sinus tachycardia, from April 1, 2022, to April 31, 2023. Septic shock was defined according to the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). VAP was identified as per the guidelines provided by the American Thoracic Society and Infectious Diseases Society of America.
Exclusion
- Patients were excluded if they had contraindications to beta-blockers, had a history of heart failure, or had been receiving beta-blockers prior to the septic shock. Patients were also excluded if they developed complications from beta- blockers administration.
Key Trial Info
Start Date :
April 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 10 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06592547
Start Date
April 1 2022
End Date
November 10 2024
Last Update
January 29 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Alexandria Main university hospital
Alexandria, Egypt