Status:
ACTIVE_NOT_RECRUITING
Skin Surface and Intradermal Temperature Responses to Heat Stress
Lead Sponsor:
University of Texas Southwestern Medical Center
Conditions:
Hyperthermia
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The purpose of this study is to compare surface and intradermal skin temperature responses to heat stress with and without evaporative and convective cooling.
Detailed Description
Humans have important thermoregulatory responses aimed at maintaining body temperature within a narrow range. These responses are driven in part by receptors located in the skin that monitor temperatu...
Eligibility Criteria
Inclusion
- Free of any significant underlying medical problems based upon a detailed medical history and physical exam.
- Normal resting electrocardiogram.
Exclusion
- Known heart disease; other chronic medical conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, and uncontrolled hypertension, etc.; as well as serious abnormalities detected on routine screening.
- Individuals who are pregnant, planning to become pregnant, or breastfeeding.
- Taking prescribed medications (such as beta blockers and non-dihydropyridine calcium channel blockers) or over-the-counter medications that have known influences on thermoregulatory response.
- Current smokers, as well as individuals who regularly smoked within the past 3 years.
Key Trial Info
Start Date :
October 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2026
Estimated Enrollment :
9 Patients enrolled
Trial Details
Trial ID
NCT06593067
Start Date
October 1 2024
End Date
October 1 2026
Last Update
July 16 2025
Active Locations (1)
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1
Institute for Exercise and Environmental Medicine
Dallas, Texas, United States, 75231