Status:

NOT_YET_RECRUITING

Clinical Study of Intestinal Barrier Dysfunction After Gastrointestinal Surgery

Lead Sponsor:

The Second Affiliated Hospital of Kunming Medical University

Conditions:

Intestinal Barrier Dysfunction

Eligibility:

All Genders

18-80 years

Brief Summary

The goal of this observational study is to explore the clinical influences associated with the development of intestinal barrier dysfunction in patients undergoing gastrointestinal surgery. The main q...

Eligibility Criteria

Inclusion

  • men or women aged 18-80 years
  • expected feasible abdominal surgical treatment (partial gastrectomy, colorectal resection)
  • no preoperative intestinal barrier dysfunction
  • patients voluntarily participated in this study and signed an informed consent form.

Exclusion

  • Patients or their families refused to participate in this study
  • chronic inflammatory diseases (e.g. inflammatory bowel disease, chronic hepatitis, chronic pancreatitis, chronic peptic ulcer, etc.)
  • history of antibiotic administration in the last 2 weeks
  • severe cognitive impairment and other inability to cooperate preoperative neoadjuvant radiotherapy
  • combined with severe hepatic, renal, and cardiac insufficiency patients.

Key Trial Info

Start Date :

October 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

April 1 2025

Estimated Enrollment :

180 Patients enrolled

Trial Details

Trial ID

NCT06596070

Start Date

October 1 2024

End Date

April 1 2025

Last Update

September 19 2024

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